“Are you ready for that jiggle, that wiggle and everything in the middle?” Lizzo asks at the beginning of her Prime Video series “Lizzo’s Watch Out for the Big Grrrls,” launcing March 25.

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It’s a question — but also a challenge to the people who believe size matters when it comes to dancing.

“Big girls are doing it, honey,” she says.

Lizzo, the pop superstar who was raised in Houston, is host, judge, mentor, cheerleader and narrator for the eight-episode series. It follows 13 dancers vying for a position as one of her “Big Grrrls,” the group of plus-size women who accompany Lizzo onstage and in music videos.

The series kicks off a new era for Lizzo that includes a new single, “About Damn Time,” dropping April 14. She’ll alsohost and performon the April 16 episode of “Saturday Night Live.” Lizzo attended and played in the band at both Alief Elsik High School and the University of Houston. She has frequently said she found her voice in Houston hip-hop.

“Watch Out for the Big Grrrls” is expectedly inspiring but also lots of fun to watch. It’s at its frequent best upending reality TV tropes: squashing drama instead of exploiting it, espousing positivity instead of manufactured toxicity. Dance is celebrated as an outlet for everything from joy to trauma.

The women are tested through a dance battle that narrows the field from 13 to ten in the first episode. They’re moved into a lavish L.A. mansion and put through a series of auditions, rehearsals and performances.

The goal? To join Lizzo onstage at the Bonnaroo Music & Arts Festival in Tennessee. There is room for all of them, she says, but they must prove they’re ready. There is, however, a problem the series will likely address closer to the finale. Lizzo was to be the festival’s first female headliner, but the 2021 edition was canceled because of heavy rains from Hurricane Ida. She is not on the 2022 lineup.

Crystal, a 24-year-old single mom from Houston, arrives with an impressive resumé. She has appeared on the MTV show “Wild ‘n Out” and danced in a Megan Thee Stallion music video. Lizzo immediately sees huge potential.

“From the moment I saw Crystal, I saw a Big Grrrl,” Lizzo says. “Crystal exudes big girl energy, and I love it.”

Sydney, also 24 and from Houston, is among the ten dancers who move into the house. She has a big social media following, and Lizzo is a longtime fan. Though she struggles with self-confidence and a sprained ankle, Sydney shines when its most important.

Jayla, 33, is a former gymnast and trans woman who can flip and split and tumble with wild abandon. But her nerves sometimes short circuit her talent. Her unassuming demeanor makes her one of the show’s most endearing personalities.

“The world just kind of looks at you and doesn’t expect you to be able to do what I’m striving to do,” she says.

That confession encapsulates the series and is what drives all of these women, who have come up against resistance and hostility in a world still clinging to unrealistic body and beauty standards. It’s something Lizzo has has built her career on and what makes “Watch Out for the Big Grrrls” must-watch TV.